What is a genital ulcer?

07/20/2022

Genital ulcers are small wounds that can form on your vagina, penis or anus. The most common cause is sexually transmitted infections, but there are many other potential causes. With successful treatment, you can make a full recovery.

1. What is a genital ulcer?

An ulcer is a slow-healing sore. It typically occurs along your digestive tract, including your stomach. But ulcers can also form in your genital area on the:

Anus.

Outer part of your vagina (vulva).

Penis.

Skin near these areas.

How do ulcers form?

Ulcers often form due to viruses, bacteria and germs that irritate the genitals’ sensitive tissue. The body responds by releasing special cells that worsen the irritation. This causes small sores to develop. Once you have an ulcer, ongoing bacteria exposure makes it difficult for the ulcer to heal.


2. Who is more likely to experience genital ulcer disease?

Anyone can get genital ulcers. Sexually transmitted infections (STIs) raise your risk of experiencing genital ulcers.

What causes genital ulcers?

The most common cause is STIs. Ulcers in the genital area can form if you have:

Chancroid, which is a bacterial disease that causes open sores.

Chlamydia.

Genital herpes.

Human immunodeficiency virus (HIV).

Syphilis.

Noninfectious ulcers like aphthous ulcers (like canker sores) or Behçet's disease.

What causes nonsexually acquired genital ulceration?

Causes of genital ulcer disease not due to STIs include:


Viruses

Cytomegalovirus, which causes viral hepatitis, encephalitis and more.

Epstein-Barr, which causes mononucleosis (mono).

Influenza A, which causes the flu.

Paratyphoid, which causes typhoid fever.

Varicella zoster, which causes chickenpox and shingles.


Bacteria

Group A Streptococcus.

Mycoplasma pneumoniae.


Certain medical conditions, especially ones that cause long-term inflammation

Behçet's disease.

Bullous pemphigoid.

Contact dermatitis.

Crohn's disease.

Cyclic neutropenia.

Erosive lichen planus.

Pemphigus.

Vaginal yeast infections.

Vulvar cancer.


Trauma

Sexual injury, when aggressive sex or foreign objects (like sex toys) break surface tissue.

Chemical burns due to a reaction to lotion, hair removal cream or skincare products.

Constant rubbing, such as undergarments that are too tight.

3. What do genital ulcers look like?

In early stages, ulcers in your genital area may look like small bumps or a rash. You may also notice swollen lymph nodes in your groin. Ulcers worsen over time, leading to small breaks in surface tissue. They may also ooze pus or fluid.


4. What do ulcers in the genital area feel like?

Some genital ulcers cause no symptoms. Others are painful and make it challenging to go about your daily life. You may experience:

Burning sensation.

Fever.

Itchy genitals.

Painful urination or sexual intercourse.

Vaginal discharge that may smell bad.

When should I see a healthcare provider about genital ulcer disease?

Talk to your healthcare provider if you experience painful genital ulcers or other symptoms. Ulcers don’t go away on their own. It’s nothing to feel ashamed of or embarrassed about. Abnormal lesions in the genital region are surprisingly common. And your healthcare provider is there to help you.